In honor of my late grandfather Vladimir Bugo. May his soul rest in peace 

We provide cash incentives for childhood vaccinations. It’s one of the most cost-effective ways known to save lives.


New Incentives’ mission is to save lives in a way that does the **most good per dollar**.
Guided by evidence, we provide cash incentives to increase childhood vaccination rates.

- We [raise awareness](https://www.newincentives.org/blog-posts/awareness-activities) about the benefits of childhood vaccinations.
- We [provide cash incentives](https://www.newincentives.org/blog-posts/a-day-in-the-life-abubakar-aliyu-field-officer) at government clinics after children receive vaccinations.
- We [help improve the vaccine supply chain](https://www.newincentives.org/blog-posts/supporting-government-partners-with-vaccine-supply-efforts) to ensure enough vaccines are available at clinics.

Together, these efforts are proven to double vaccination rates and save lives.
Learn more about the [randomized controlled trial](https://www.newincentives.org/rct-results).

As of March 2024, New Incentives has reached more the 3 million infants in northern Nigeria.

New Incentives

We are a research hospital that treats patients in all medical disciplines, focusing on oncology, neurology, and diagnosis.

The Fondazione Casa Sollievo della Sofferenza – Opera di San Pio da Pietrelcina (transl. Home for the Relief of Suffering Foundation – Work of Saint Pio of Pietrelcina) is a not-for-profit research hospital located in the city of San Giovanni Rotondo (FG), in the Puglia Region, Southern Italy.
As per Canon 1303 §1 of the Code of Canon Law, it has public, canonical and civil legal personality; it is therefore subject to the supervision of the Holy See and, on its behalf, of the pro-tempore Cardinal Secretary of State. 
Many of the stages that have thus far marked the history of the Work of San Pio of Pietrelcina have been achieved thanks to the loving generosity of many benefactors who, sharing the mission indicated by San Pio da Pietrelcina, the relief of suffering, wanted to donate to his work.

HISTORY
The hospital was founded and inaugurated by Saint Pio of Pietrelcina on May 5, 1956 with a capacity of 250 beds. It took on the status of Provincial Hospital on 4 August 1971 and then of Regional General Hospital on 2 June 1980, thus becoming part of the Italian National Healthcare System. Since 16 July 1991, with a Decree of the Minister of Health and the Minister of University and Scientific Research, it has been a Research Hospital. Originally, the object of its scientific activity was limited to genetic and hereditary-familial diseases; subsequently, the Minister of Health, by the 5 December 2012 Decree, extended the research areas of its competence to "Genetic diseases, innovative therapies and regenerative medicine". Recently, on the occasion of the presentation of the research lines for the three-year programme of the Italian Research Hospitals 2022-2024, Casa Sollievo identified “Diagnostic acitivity, Neurology and Oncology” as its main research thematic areas, thus becoming a polythematic Research Hospital.

MISSION
The Foundation's mission is to provide health care and carry out research activities. In addition, the Foundation offers training activities for its personnel.
Around 2,750 people work at the Foundation.
The Foundation (hereinafter “CSS”) consists of three structures based in San Giovanni Rotondo: the hospital Casa Sollievo, the polyclinic Giovanni Paolo II, where outpatient activities are carried out, and the ISBReMIT research center for regenerative medicine (Institute for Stem-cell Biology, Regenerative Medicine and Innovative Therapies); and the Mendel Institute in Rome, where research and diagnostic activities are carried out. In San Giovanni Rotondo, it also owns and runs a retirement home for the elderly.
In addition, CSS owns 3 hospitality facilities where affordable accommodation is offered to hospitalized patients’ relatives who have to assist them; and another facility (Casa Zeni) where accommodation is offered free of charge to the parents of the little patients hospitalized in the oncology-hematology unit.
Moreover, the Foundation includes the Padre Pio Prayer Groups Centre, which was also founded by San Pio and coordinates the Padre Pio prayers groups throughout the world, according to the Founder’s wish that Prayers Groups live and testify the importance of prayer and pray for CSS.
Lastly, CSS publishes a monthly periodical and posts on the Foundation’s official channels on the web updates on its research and clinical activity and its spiritual activity and the teachings of the Founder.
The hospital offers assistance also to people from underdeveloped countries. 
Moreover, a free-of-charge shuttle service has been provided for many years to radiotherapy patients coming from Bari and surrounding cities (Southern Puglia).

THE CLINICAL ACTIVITY
CSS has around 756 beds, 38 medical and surgical inpatient units, 26 operating rooms, in addition to services, diagnostic and multi-specialist outpatient units.
In 2022, the hospital recorded over 30,000 hospitalizations and 870,000 outpatient performances. 
Regarding the advanced technological equipment, CSS has 1 "Da Vinci" surgical robot, 1 PET/CT device, 3 linear accelerators, 4 CT devices, 1 CT simulator for radiotherapy, 4 NMR equipment, 3 digital angiographs, 2 gamma cameras and a RIS/PACS system for the filmless management of the radiology department.
Furthermore, CSS hosts an Umbilical Cord Bank and a Human Milk Bank.
Recent Achievements
In addition to the many important activities carried out in CSS, 3 new units have been opened: 1. a new Emergency Room hosting an Observation and Assessment Ward; 2. an Hematopoietic Stem Cell Transplant Center. 3. an Sub-Intensive Geriatric Unit. 
CSS has also established a Stroke Unit, a Lung Unit, a Breast Unit, a Head and Neck Unit, and a Molecular Tumor Board to guarantee appropriate, quality and homogeneous procedures.
Future goals
Important technological investments have been planned for the years 2023-2025 in the following areas: oncology/nuclear medicine, diagnostic imaging, ICU, and surgery. 

THE RESEARCH ACTIVITY
The research activity is conducted in the Polyclinic, the ISBReMIT research center and at the Mendel Institute, for a total of 17 research groups.
Recent achievements
The consolidated experience of the staff working in CSS in the study of genetic diseases since 1991 and the continuous updating of technologies, instrumentation and genomics and post-genomics skills have made it possible to direct the research and clinical-assistance activity towards two complementary research lines: "personalized medicine - system biomedicine" and "regenerative medicine" based on the study of tumor stem cells and the use of normal stem cells.
The scientific fields in which the Institute is mostly involved in "personalized medicine" concern the identification of the genetic causes of rare diseases and the identification of diagnostic, prognostic and predictive markers in complex pathologies, including tumor pathologies. Regarding the identification of the genetic causes of rare diseases, we use the new next generation sequencing (NGS) technologies and the skills acquired by the bioinformatics unit, one of the first established at national level. In parallel, the Institute boasts a large collection of induced pluripotent stem cells (iPSCs), produced from patient fibroblasts, in which pathogenetic variants have been identified, and use the skills acquired in differentiating them into mature cells, in particular astrocytes, neurons and oligodendrocytes.
Regarding regenerative medicine, two important studies were conducted and concluded: a phase I trial on anti-Multiple Sclerosis therapy based on the use of human neural stem cells, approved by the Ministry of Health and the Italian Medicines Authority AIFA (EudraCT code 2015-004855-37); and a phase I/II trial on anti-glioma therapy with biological drugs (EudraCT code: 2016-001761-92). The results of these studies will published in prestigious international journals.
In 2015, the new ISBReMIT Regenerative Medicine Research Center was started. It is a cutting-edge structure in terms of conception and equipment in the field of translational medicine for genetic, degenerative and oncological diseases. The structure hosts, together with the highly technologically equipped laboratories, a cell factory and a laboratory for the production of biopharmaceuticals under Good Manufacturing Practice, i.e. for clinical use, including somatic stem cells and iPS, vectors for gene therapy and biomaterials.
It should be noted that CSS has recently become part of three Networks of the Italian Research Centers: since 2016 it has been an Ordinary Associate of Alleanza Contro il Cancro; since December 2018, of the National Research Network on Aging; and, finally, since March 2020 of the Neuroscience Network. Starting from 2022, CSS has been part of the European reference networks for rare and uncommon diseases (European Reference Networks - ERN), in particular ERN-SKIN on diseases of dermatological interest, and ERN ReCONNET on musculoskeletal diseases and pathologies of the connective tissue.
Researchers publish about 200 scientific articles in the most renowned journals (Science, New England Journal of Medicine, Nature Genetics) every year. They are engaged both as Principal Investigators and as partners in research projects in the biomedical field and ICT, obtaining funds from the EU (H2020 and FP7) and national or regional calls.
CSS is also a partner in Research and Innovation projects funded by private and public bodies, e.g. from the EU both under Horizon 2020 and Horizon Europe, in the field of digital transformation of healthcare. The main areas of involvement concern Assistive Robotics, Artificial Intelligence, Big Data generated by consumer devices, eHealth, Digital Therapies, the Internet of Things and Cybersecurity.
Future goals
Starting from the identification of the genetic causes of diseases, the goal is to develop advanced therapies to bring to the patient's bedside and tailored to him/her.
Furthermore, at the end of 2023, the phase II study "Neural Stem Cell Treatment for Amyotrophic Lateral Sclerosis: A multicenter, randomized placebo controlled and biological endpoints clinical Trial" (EudraCt 2018-002373-22) will be launched. This involves the use of neural stem cells on patients suffering from Amyotrophic Lateral Sclerosis.

CONCLUSION
Casa Sollievo della Sofferenza was born of the visionary mind of a poor friar, one of the most important, recent and internationally recognized and prayed Saints, Saint Pio of Pietrelcina, right after the II World War, in a poor corner of the Southern Italy of those times. 
CSS, by its Statutes, is a not-for-profit organization. All the good work that has been done until now for the sick has been possible thanks to the generosity of donors and to the public and private funds that have been collected through the hard work of the Foundation’s researchers and clinicians, thus contributing importantly to the care of citizens from Southern Italy and underdeveloped countries and to the world research.

Fondazione di Religione e di Culto Casa Sollievo della Sofferenza - Opera di San Pio da Pietrelcina

High quality medical services for marginalized groups in Cairo and the region.

Mersal Foundation for Charity and Development is a non-profit organization that serves in the health field and works on providing all types of healthcare with high quality to whoever is in need.

**Vision**
To be the number one medical organization in Egypt and the Arab region and proactive in ensuring the right in healthcare for the marginalized groups and those who are in need the most.

**Message**
Working on analyzing and filling the gaps of the healthcare system to provide high quality medical services on the basis of equality and dignity through enabling a charitable healthcare system for whoever cannot afford it, as well as contributing to the development of the health sector.

**Objectives**  

- Providing medical services to whoever deserves them regardless the cost or for how long they will be needed.
- Spreading medical awareness in all the places it serves in.
- Achieving sustainability in funding its activities Core Values.
- Privacy: Mersal ensures the patient's eligibility to receive its services without hurting their dignity or exposing them to any kind of embarrassment.
- Healthcare With No Discrimination: Mersal is an open arm to all patients with no discrimination whatsover; whatever religion, nationality, color, or language, all patients in need are welcomed to receive the organization services.
- High Quality: Mersal provides all types of medical services in the highest possible quality through its network of specialized medical personnel.
- Credibility and Transparency: Mersal announces the size and sources of its fund as well as its administrative and medical expenditures, The foundation financial reports and annual budgets are available through several outlets through which any person can explore how resources are managed. Mersal believes in the importance of being specialized in specific fields and its early choice was the healthcare services.

In the past six years, the organization registered over 25,000 patients from 27 provinces.  Mersal has been seeking to enable access to its services all over the country. And the dream of helping those who are in need whoever they are and whatever the cost and time is still alive, Mersal has worked over the past six years on getting close to its patients throughout their treatment journey.

Mersal Foundation for Charity and Development 

Sentinel transforms pandemic prevention and response through cutting-edge technology, global collaboration, and local empowerment.

Infectious disease outbreaks have caused more illness, death, and economic loss than any other crisis in history. Pathogens kill millions of people each year and hit the most vulnerable communities the hardest. They go further—exposing and exploiting the deepest cracks in our societies and the risks are rising. 

 The forces driving pandemics are accelerating. Climate change is increasing human exposure to pathogens through animals and insects. Habitat encroachment and industrial agriculture are raising the risk of spillover. Global trade and travel speed disease spread, while conflict and instability weaken health systems. New biotechnologies pose engineered threats that current systems cannot detect. Over the past decade, the number of epidemics has grown by 20% worldwide. Between February and June 2025 alone, more than 70 outbreaks were reported across Africa. Yet global readiness is faltering. In the past year, U.S. investments in frontline health systems and disease surveillance have been sharply reduced. Funding cuts have disrupted networks and delayed the deployment of critical tools, especially in regions most vulnerable to outbreaks. Health programs across West and Central Africa now face rising threats with fewer resources and limited external support, leaving the world more exposed- with some experts estimating the probability of a pandemic in the next decade to exceed one in four.
 
Amid these mounting challenges, we stand at a historic moment of possibility. Sentinel, a pandemic early warning prevention and response program, is built to meet this moment: a locally led, technology-enabled model for proactive public health, integrating diagnostics, data, and training to stop outbreaks before they spread. 

Sentinel is an outbreak surveillance framework, designed to detect pathogenic threats in real-time and prepare the global community to stop diseases before they spread. It brings advanced science to the frontlines through a next-generation pandemic prevention system built around three core pillars. DETECT delivers rapid diagnostics and genomic surveillance. CONNECT integrates laboratory, clinical, and genomic data into real-time insights. EMPOWER invests in training, infrastructure, and institutional capacity so countries can lead their own outbreak responses.

DETECT: Timely diagnostics and sequencing are essential for early outbreak detection and effective response. Yet these capabilities remain limited in many LMICs, even for high-priority pathogens like Lassa, Ebola, and Marburg. Too often, health systems act only after outbreaks are widespread, costing precious time and lives. Sentinel’s DETECT pillar delivers speed, affordability, and accessibility through a tiered approach to diagnostic design and implementation.

CONNECT: Fragmented systems delay response and allow outbreaks to spread unchecked. When data are siloed, public health leaders lose time and visibility, undermining containment efforts. In contrast, integrated systems support faster, more effective action. Sentinel’s CONNECT pillar builds the digital backbone for outbreak response. Through interoperable dashboards and analytic platforms, it streamlines data flow, strengthens each stage of detection, analysis, and control, and enables real-time decision-making.

EMPOWER: Building local leadership and scientific capacity is central to Sentinel’s mission. Although over 60% of emerging infectious diseases originate in Africa and Asia, fewer than 10% of African countries had genomic surveillance at the start of COVID-19. Africa faces a shortfall of more than one million health workers, including critical gaps in genomics and data science. Sentinel’s EMPOWER pillar builds sustainable, locally led outbreak response by investing in people and communities. It enables local experts to detect and respond early with solutions grounded in context, shortening the path from innovation to public health practice and building resilient systems from within.

The foundation for Sentinel was laid over two decades through a 20-year partnership between Prof. Christian Happi, a Nigerian infectious disease expert, and Prof. Pardis Sabeti, a U.S.-based computational geneticist. Over the years this collaboration has established operational programs in Nigeria and Sierra Leone that connect health workers in rural clinics and hospitals with national and international public health leadership. **To date more than 3,000 public health workers from 53 of 54 countries in Africa** have been trained through Sentinel’s approach.

Sentinel-supported teams have enabled early detection and rapid response to Marburg, mpox, Lassa, dengue, and COVID-19, providing critical data to inform government action. 

COVID-19: Sentinel rapidly expanded genomic and diagnostic capacity across Africa, establishing pipelines with national partners. In March 2020, IGH sequenced Africa’s first SARS-CoV-2 genome within 72 hours of sample receipt. Sentinel supported testing for over 30 million people, deployed SHINE and CARMEN technologies, and led genomic surveillance in 26 countries. This work helped identify one of the first globally recognized variants of concern. Sentinel also trained scientists from 53 African countries, strengthening long-term preparedness. The Sentinel team also led one of the largest diagnostic and sequencing centers in the U.S. and supported global data sharing and informatics efforts.

Mpox: In 2023, Sentinel traced an mpox outbreak in Nigeria to oil workers in Rivers State, guiding the NCDC’s targeted vaccination strategy. Sentinel also hosted a three-week genomics bootcamp that trained regional professionals in real-time sequencing and analysis. Genomic data revealed sustained human transmission of the West African subtype, with signs of adaptation and rising pandemic potential. When an outbreak emerged in Sierra Leone in 2024, local public health teams, supported by Sentinel, initiated sequencing and shared real-time data. Analysis identified a new highly transmissible G.1 variant spreading beyond previously affected groups. Sentinel tools and team members remain central to guiding the national response.

 Marburg: In 2024, Sentinel supported the Rwandan government during a Marburg outbreak in Kigali. IGH provided outbreak reconstruction and real- time sequencing, while Prof. Happi co-chaired the national scientific response. The outbreak was contained at 66 cases, with the case fatality rate reduced to 22%, far below historical averages.

Building off of these successes, Sentinel is poised for its next phase: deepening national integration, expanding its reach, and advancing a globally transferable model for pandemic prevention. We will achieve full national implementation in Sierra Leone and move toward this in Nigeria, embedding surveillance into national systems and incorporating a One Health approach that addresses climate-linked and zoonotic threats. Expansion will continue to Senegal, Rwanda, and the Democratic Republic of Congo, where strong partners and readiness are in place. In parallel, we are globalizing Sentinel’s tools, data platforms, and training programs to create a lasting framework for pandemic prevention.

Sentinel will help millions benefit from earlier detection, faster response, stronger systems, and a globally connected early warning network. This is the moment to transform pandemic prevention and safeguard global health security for generations to come.

There will be another pandemic virus in our lifetimes—it may already be here, but our work is about more than stopping disease outbreaks. By empowering people and equipping them with the tools, the system, and the knowledge needed, we create strong and resilient communities for generations to come. Sentinel is about partnership, solidarity, and most importantly, hope!

That's why we believe that with you, we can make an impact.

Sentinel 

Improving health in the Peruvian Andes by training and empowering indigenous women as community health workers. 

Sacred Valley Health is a community-based, public health nonprofit that partners with vibrant, indigenous communities in the Andes of Peru. **Our core purpose is improving  health and well-being in underserved, marginalized communities through a community health worker program that empowers local women with education, resources, professional development, and economic opportunities.** 

Sacred Valley Health works with **marginalized partner communities to increase access to health knowledge and health care while \***providing vocational training to women and elevating them as leaders within their communities\*.\*\* It is often the case in indigenous communities, like SVH’s partner communities in Peru, that older women viewed as community elders are a respected voice when it comes to dictating community norms. ​​Our vision is that by empowering cohorts of women with health education and vocational training and by providing culturally relevant health information and care to the vibrant, indigenous partner communities we partner with, we can help people living in these communities to experience greater health and well-being.  

Since its inception in 2012, Sacred Valley Health has trained more than 100 women as health workers, launched a very successful train-the-trainer program, and developed a customized, comprehensive health education curriculum for visual Quechua-speaking learners. Most importantly, Sacred Valley Health has become a trusted, reputable partner in the local health landscape - among community members, health officials, funders, and other nonprofits - by using a collaborative, participatory approach in their work.

Sacred Valley Health

Whole Child International is a nonprofit, international child protection and development organization founded in 2004. 

Whole Child International works collaboratively with local partners, governmental and non-governmental, to ensure that children receive the quality of care they need to grow into resilient, productive citizens, regardless of where they live.  We use an evidence-informed approach, drawing on cutting edge child development research, to train caregivers, child protection authorities, and government actors to ensure the entire child protection and development system is focused on ensuring positive outcomes for the most vulnerable children.  

Our work in Nicaragua and El Salvador produced statistically significant improvements in cognitive and social functioning, as well as weight- and height-for-age, without substantial changes to the material environment or their diets.  We change the behavior of the adults around the children to provide relationship-centered care and transform children's developmental trajectory.  Developmentally supportive care in childhood is associated with better educational, economic, health (physical and mental), and social outcomes later in life; that is, providing quality care for today's children helps reduce poverty, conflict, and social inequities in the future.  

Women and children are disproportionately affected by violence, climate change, and poverty; they are also key to disrupting these harmful cycles.  Our approach strengthens families, both biological and not, by equipping caregivers with the skills they need to care for their children's holistic needs, emotional, developmental, nutritional, etc.  We work with childcare centers and providers in low-income and high-violence areas to improve the quality of care available to children who might otherwise not have access to these services.  We especially work with women -- both caregivers and those working in the child protection system -- to develop their capacity as community leaders and models for positive change.   

At Whole Child International, we Embrace the Future.

Whole Child International

Our mission is to protect LGBTQ+ youth in Poland from the harms of homelessness and refugeehood. 

The Warsaw House Foundation's mission is to protect homeless and refugee  LGBTQ+ youth in Poland and provide them with the tools they need to live independently. Our inspiration was the  Ali Forney Center  (AFC)  n NYC, which is largest organization in the world offering support to homeless LGBTQ+ youth. We are honored that Carl Siciliano, the AFC's founder is on the board of the Warsaw House Foundation and works as an advisor. We place extra attention on HIV and STI education, support and prevention with the help of board member Dr. Joanna Kubica and the Smart Life Clinic in Warsaw.  After we took in our first LGBTQ+ youth to house on February 14th, 2023  we have been flooded with calls for housing and support from young people in need.  These are Polish Trans 18 year-olds from the Polish countryside in desperate need to escape their abusive and intolerant homes, young queer people with PTSD and untreated mental illness who need housing and support immediately, LGBTQ+ refugees from Ukraine and several young gay men from Iraq who suffered torture in their homeland, were detained and imprisoned at the Polish/Belarussian border for up to two years, and are now trying to build their lives in Poland.  We are also housing and supporting young LGBTQ+ people from Uganda and Egypt,  We are raising money to support the young people under our care, to house and feed them and pay for their medical needs and courses needed for them to start an independent life,  We are also raising money to hire staff (all of WH's work is now done by volunteers), to continue the renovation of our residential building and for short term emergency rentals.  We have a committed and professional team and a well planned strategy for both emergency and long term care.  Any help would be greatly appreciated!! We will be in regular contact if you'd like to hear of our progress and  if you'll be in Warsaw, we'd be delighted to meet with you personally and show you the work we do.

Warsaw House Foundation

We target opportunities where small investments can generate extraordinary impact and create lasting change.

There are many charities that address global poverty and suffering. 

With our Global Health & Development (GHD) **Catalytic Impact Fund**, we try to find the strategic pressure points where modest funding unlocks transformational change. 

By prioritizing these leverage points, we help donors maximize their impact in building sustainable, long-term solutions to global poverty and suffering — saving and improving as many lives as possible with each dollar.

What does catalytic impact look like?

- **We trigger systemic improvements**: We support investments that create new long-term infrastructure or increase the cost-effectiveness of existing systems.
- **We remove key bottlenecks**: We identify and remove barriers that stand in the way of accelerated impact.
- **We crowd in capital**: We provide early-stage funding that attracts substantial follow-on investment for cost-effective opportunities.

### Our Approach to Grantmaking

When evaluating potential grants, we consider several key points:

- **Counterfactual impact**. Our grants are designed to create meaningful outcomes that would not otherwise have happened. This means that you can rely on the Funds to create meaningful, real change, rather than just maintaining the status quo.
- **Impact-driven philanthropy**. This fund prioritizes the highest-impact solutions to challenges. We assess where the gaps are, which opportunities may be neglected by other funders, and where the biggest wins are in terms of making the biggest difference.
-  **The organization’s funding gap**. Not all organizations are set up to scale programs and some may not be able to productively absorb large amounts of unsolicited funding at any given point. We evaluate all potential grantees’ capacity for growth and consider how much money they could put to good use.
-  **Organizational strength**. Particularly with unrestricted funding, it’s important to have trust in the leadership and capacity of the organizations we support. We look at their track record of success and their transparency about failures as well as successes, and we only support those organizations which are exceptionally well run.
- **Time-critical opportunities and funding certainty**. Sometimes there are time-critical opportunities which require fast decisions. We will use the Fund to make grants that enable such short-term opportunities and stability for high-impact funding opportunities thereby increasing the impact compared to individual giving to specific organizations.

### Frequently-Asked Questions

**Can charities apply for money from the Fund?**

Founders Pledge reviews [requests for funding](https://www.founderspledge.com/requests-for-funding) from organizations, but does not guarantee we can fill funding requests.

**How frequently will you make grants from the Fund?**

In general, Fund Managers will review grantmaking decisions on a quarterly basis, based on the value of Funds and the available options for high-impact grantmaking. We may disburse funds outside of quarterly review dates if we become aware of a particularly promising and time-sensitive funding.

**How will my contribution be used?**

All funds are granted out — every dollar contributed to the Fund will be used to make grants directly to end-user organizations creating a real difference.

### More Questions?

To learn more about the Founders Pledge GHD Catalytic Impact Fund, please visit [founderspledge.com](https://founderspledge.com/funds/global-health-and-development-fund) or email the team at [funds@founderspledge.com](mailto:funds@founderspledge.com).

Founders Pledge: GHD Catalytic Impact Fund

LifeStraw operates the Safe Water Fund, a 501(c)3 project, to support the provision of safe water where it is needed most.  

The Safe Water Fund operates as a 501(c)(3) project, supporting the implementation of long-term, sustainable safe water programs worldwide. We partner with grassroots organizations and local leaders to identify and reach communities and families most in need.

In addition to our retail-funded Give-Back program, the Safe Water Fund provides safe water during humanitarian emergencies and natural disasters. We also lead special initiatives in the cities where our employees live, including at our headquarters in Baltimore City, and participate in Giving Tuesday efforts each year.

**100% of donated funds go directly toward products and the distribution of safe water supplies. Vestergaard Frandsen, Inc. (d/b/a “LifeStraw”) does not profit from your donation.**

*The Safe Water Fund operates through a fiscal sponsorship with Players Philanthropy Fund, a Texas nonprofit recognized by the IRS as a tax-exempt public charity under Section 501(c)(3) of the Internal Revenue Code (Federal Tax ID: 27-6601178, ppf.org/pp). Contributions to the Safe Water Fund qualify as tax-deductible.*

Your contribution helps us bring safe drinking water to more families. 

Thank you for your support!

LifeStraw Safe Water Fund

Phare Bio is using AI/deep learning to discover novel classes of antibiotics to address a looming crisis in antibiotic resistance.

Phare Bio is an ambitious social venture using novel AI and deep learning approaches to antimicrobial development in collaboration with Professor Jim Collins at MIT, a founder of the field of synthetic biology. Phare is a recipient of the Audacious Project, a collaborative funding initiative between TED and other non-profits to unlock social impact on a grand scale. 

The rapid evolution of antibiotic-resistant bacteria and a dwindling discovery pipeline have resulted in an antimicrobial resistance (AMR) crisis. Today, according to the Centers for Disease Control and Prevention, someone in the U.S. acquires a resistant infection every 11 seconds; every 15 minutes someone dies as a result of one. Covid-19 has only highlighted the urgency with approximately 15% of hospitalized patients suffering from bacterial co-infections. There is a critical need for new antibiotics, and yet, pharmaceutical and biotechnology companies have largely abandoned the space in favor of more lucrative markets. 

Phare Bio launched in 2020 to tackle this critical unmet need with the latest advances in machine learning to develop entirely novel antibiotics. Integrating world-class expertise and decades of experience in artificial intelligence (AI), bioengineering, and life sciences, Phare is targeting the world's most deadly pathogens, such as Acinetobacter and Pseudomonas, with the goal of developing seven novel classes of antibiotics in seven years. 

Phare Bio

Founders Pledge is a global nonprofit empowering entrepreneurs to do the most good possible with their charitable giving. 

Maximize your philanthropic impact with Founders Pledge. We empower a global community of over 2,100 members, equipping them with everything needed to give effectively: from evidence-led research and expert advice on the world's most pressing problems to comprehensive infrastructure for seamless global grant-making, and a powerful network for collaboration. Together, we've already channeled over $1.5 billion to high-impact causes globally, tackling critical issues like climate change, global health, and emerging existential risks. 

When you donate through every.org today, you're joining this proven movement, and our unique funding model ensures 100% of your contribution goes directly to charity, as our operational costs are generously covered by a dedicated community of philanthropists.

Donate this Giving Season and we'll match your donation up to a value of $750,000, until Dec 31.

Founders Pledge

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.css-1wjgqn{display:inline-block;--textSize:1.5rem;--lineHeight:1.7999999999999998rem;line-height:var(--lineHeight);font-size:var(--textSize);width:100%;}Disease Prevention

New Incentives

Mersal Foundation for Charity and Development

Fondazione di Religione e di Culto Casa Sollievo della Sofferenza - Opera di San Pio da Pietrelcina

Mersal Foundation for Charity and Development

Mersal Foundation for Charity and Development

Mersal Foundation for Charity and Development

Disease Prevention