Understanding how knowledge grows (the primary concern of epistemology) is one of the most fundamental questions that humanity has ever asked. Because the growth of knowledge plays a role in every human endeavor–from science to politics to creating artificial intelligence to raising children to entrepreneurship–getting the answer wrong necessarily leads to blind alleys and errors. Fortunately, Karl Popper, David Deutsch, and other thinkers have discovered and elaborated upon the right answer: that knowledge grows via conjecture and criticism.
Such a simple idea (the entire theory of which is called critical rationalism) has an enormous number of practical implications for all of the aforementioned fields and any other in which humans can make progress. While the revolutions brought forth by Newton, Darwin, and Einstein were profound and improved mankind's lot in the universe, even they were limited to particular strands of human endeavors. But epistemology is universal for any problem a person or society faces. Therefore, spreading critical rationalism and its implications will dissolve barriers to progress that most people do not even know stand in their way.