One of GiveWell's top charities for the past several years, AMF provides anti-malarial bednets to people in need. 

From Givewell: 
What do they do? AMF (againstmalaria.com) provides funding for long-lasting insecticide-treated net (LLIN) distributions (for protection against malaria) in developing countries. (More)

Does it work? There is strong evidence that distributing LLINs reduces child mortality and malaria cases. AMF conducts post-distribution surveys of completed distributions to determine whether LLINs have reached their intended destinations and how long they remain in good condition. AMF's post-distribution surveys have generally found positive results but have some methodological limitations. (More)

What do you get for your dollar? We estimate that the cost to purchase and distribute an AMF-funded net is $4.95, or $4.65 excluding in-kind contributions from governments. The numbers of deaths averted and other benefits of distributing LLINs are a function of a number of difficult-to-estimate factors, which we discuss in detail below. (More)

Is there room for more funding? We believe that AMF is likely to be constrained by funding. We estimate that AMF could use up to an additional $37.8 million to support LLIN distributions that will occur between now and late 2023. 

AMF is recommended because of its:

Focus on a program with excellent evidence of effectiveness and cost-effectiveness.
Processes for ensuring that nets reach their intended recipients and monitoring whether they remain in homes and in good condition over the long-term.
Room for more funding – we believe AMF will be able to use additional funds to deliver additional nets.
Transparency – AMF shares significant information about its work with us and we are able to closely follow and understand its work.

The Against Malaria Foundation

The Top Charities Fund supports the highest-priority funding needs among our top charities.

We find and recommend outstanding giving opportunities and publish our research to help donors give more effectively and with greater confidence.

All donations here support our Top Charities Fund. Donations to the Top Charities Fund are granted on a rolling basis to support cost-effective funding opportunities at our top charities. We use our latest research to grant the funds to the top charity (or charities) where we believe they’ll do the most good.

Learn more and view past grants at https://www.givewell.org/top-charities-fund


Photo caption: At health centers in Sierra Leone supported by Helen Keller Intl, mothers who bring their children in for twice-yearly vitamin A supplemention can also receive comprehensive counseling about birth control options that are available to them free of charge. Combining family planning and children's healthcare services benefits both mother and child. 2019.

Top Charities Fund

We do foundational mathematical research to ensure smarter-than-human artificial intelligence has a positive impact.

The Machine Intelligence Research Institute is a research nonprofit studying the mathematical underpinnings of intelligent behavior. Our mission is to develop formal tools for the clean design and analysis of general-purpose AI systems, with the intent of making such systems safer and more reliable when they are developed.

The field of AI has a reputation for overselling its progress. In the “AI winters” of the late 1970s and 1980s, researchers’ failures to make good on ambitious promises led to a collapse of funding and interest in AI. Although the field is now undergoing a renaissance, overconfidence is still a major fear; discussion of the possibility of human-equivalent general intelligence is still largely relegated to the science fiction shelf.

At the same time, researchers largely agree that AI is likely to begin outperforming humans on most cognitive tasks in this century. Given how disruptive domain-general AI could be, we think it is prudent to begin a conversation about this now, and to investigate whether there are limited areas in which we can predict and shape this technology’s societal impact.

Researchers at MIRI tend to be relatively agnostic about how the state of the art in AI will change over the coming decades, and how many years off smarter-than human AI systems are. 

Machine Intelligence Research Institute

We provide cash incentives for childhood vaccinations. It’s one of the most cost-effective ways known to save lives.


New Incentives’ mission is to save lives in a way that does the **most good per dollar**.
Guided by evidence, we provide cash incentives to increase childhood vaccination rates.

- We [raise awareness](https://www.newincentives.org/blog-posts/awareness-activities) about the benefits of childhood vaccinations.
- We [provide cash incentives](https://www.newincentives.org/blog-posts/a-day-in-the-life-abubakar-aliyu-field-officer) at government clinics after children receive vaccinations.
- We [help improve the vaccine supply chain](https://www.newincentives.org/blog-posts/supporting-government-partners-with-vaccine-supply-efforts) to ensure enough vaccines are available at clinics.

Together, these efforts are proven to double vaccination rates and save lives.
Learn more about the [randomized controlled trial](https://www.newincentives.org/rct-results).

As of March 2024, New Incentives has reached more the 3 million infants in northern Nigeria.

New Incentives

The Centre for Effective Altruism helps to grow and support the effective altruism community.

Effective altruism is about using evidence and reason to figure out how to benefit others as much as possible, and taking action on that basis.

The Centre for Effective Altruism (CEA) is a charity dedicated to building and nurturing a global community of people who are thinking carefully about the world’s biggest problems and taking impactful action to solve them.

We hope that this community can help to build a radically better world: by connecting students and young professionals with relevant experts, we can help them consider their values and find an effective way to contribute that is a good fit for their skills and inclinations.

Centre for Effective Altruism USA

Evidence Action scales evidence-based and cost-effective programs to reduce the burden of poverty. 

Evidence Action was founded in 2013 to address a big gap in the fight against global poverty – many of the most promising interventions are either implemented at a very small scale, or not at all. We set out to address this gap by building programs that would scale evidence-based and cost-effective interventions, leading to significant improvements in quality of life for hundreds of millions of people.

Our model worked. Since then, our interventions have reached more than 530 million people. This success is achieved through the dedication and talent of our staff, the hard work of our partners, and the commitment of our supporters.

Our Accelerator is the engine for our new program development. To find the most cost-effective solutions in the world, we explore untapped opportunities with the greatest potential for impact. Through a rigorous process, we test groundbreaking health and development interventions, selecting those with a proven ability to reduce the burden of poverty at scale. This focus allows us to maximize the impact made for every single dollar invested.

**Programs:**

**Safe Water Now**

We provide sustained safe water access to communities through water treatment – one of the most cost-effective ways to prevent childhood illnesses and death. Safe Water Now programming in Kenya, Uganda, Malawi, and India uses innovative, low-cost approaches like chlorine dispensers and automatic in-line chlorination. With local government and community buy-in, we reach nearly 10 million people with safe water access and have saved the lives of more than 15,000 children under 5 years old. Now, we are scaling in partnership with the Government of India to reach tens of millions more.

**Deworm the World** 

We help improve children's health, education, and long-term wellbeing by treating parasitic worm

infections at schools. In partnership with governments in Kenya, Nigeria, India, and Pakistan, Evidence Action designs, scales, and sustains cost-effective mass deworming programs. Since 2014, Deworm the World has helped governments deliver 2 billion deworming treatments to children, dramatically reducing worm prevalence and collectively increasing economic productivity by an estimated $23 billion USD.

**Equal Vitamin Access**

We combat the leading cause of childhood malnutrition and disability in low- and middle-income countries by helping to deliver essential supplementation. Equal Vitamin Access provides end-to-end support to governments in India and Malawi to address anemia by leveraging our school-based deworming platform to offer iron and folic acid supplementation cost effectively. In 2023 alone, our program reached 35.8 million children with weekly treatments, giving them a

better chance to develop into strong, healthy adults.

**Syphilis-Free Start**

We safeguard the health of pregnant women and their unborn children by enabling access to low-cost syphilis screening and treatment as part of prenatal care. We partner with governments in Liberia, Cameroon, and Zambia to prevent disability, neonatal

mortality, and stillbirths resulting from congenital syphilis. Syphilis-Free Start’s timely detection and treatment prevented 2,300 adverse outcomes such as blindness, neurological issues, and hearing loss between 2021 and 2023, including 1,300 lives saved.



Evidence Action

Malaria Consortium

Delivering unconditional cash directly to the world's poorest households via secure mobile transfers. 

Since 2009, GiveDirectly has delivered more than $580 million in unconditional cash transfers to families in need. These one-time cash transfers allow recipients to invest in what they need most and have been shown to improve their earnings, children’s school attendance, health, nutrition, and mental well-being.
 
GiveDirectly uses government data to target villages where most or all residents are living in extreme poverty, defined by the World Bank as earning under $2.15/day. In-country GiveDirectly staff enroll one member of each household in the entire village to receive a one-time transfer of about $1,000 USD sent in two installments using mobile money. Recipients can then withdraw the mobile funds as cash with local agents and use the funds to invest in what they need – whether it’s on starting a business, education, making their home safer/sturdier, healthcare, or livestock.
 
GiveDirectly uses rigorous experimental research (randomized controlled trials) to measure the impact of their unconditional cash programs and answer public policy questions, generating evidence on key design and implementation questions across varied contexts. You can find over 300 studies on the positive impacts of cash transfers in GiveDirectly’s Cash Research Explorer.

GiveDirectly

We search for the charities that save or improve lives the most per dollar.

Our goal is to produce the world's top research on where to give. Free, for everyone.

We recommend a small number of charities that do an incredible amount of good. 

If you would like to donate to our giving funds or individual top charities, please see our projects below. You can donate here or on the Unrestricted Fund page below to make an unrestricted gift to GiveWell to support the full spectrum of our grantmaking and underwrite our ability to continue doing what we do.

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Life has been kind to me and it's my mission to share that kindness with the world. 

Every person and child deserves an opportunity to live a healthy life. The Against Malaria Foundation provides effective preventative measures for an incredibly low cost. What could be better?

We need to scale up new effective charities. I have a ton of respect for their approach, especially after hearing that they shut down their No Lean Season after collecting evidence that showed lower impact than hoped-for: https://www.vox.com/future-perfect/2019/6/7/18654620/evidence-action-no-lean-season-givewell