The END Fund is the only private philanthropic initiative solely dedicated to ending the most common neglected tropical diseases.

Our Mission: To control and eliminate the most prevalent neglected tropical diseases (NTDs) among the world's most vulnerable communities and people by 2030. 


NTDs are a group of parasitic and bacterial diseases largely prevalent in tropical regions that currently receive little attention on the global health agenda yet have a significant impact hampering the potential of individuals and communities at large. The devastating effects of NTDs include irreversible blindness, severe disfigurement, stunted cognitive and physical development, especially in children, malnutrition, social isolation, and more. NTDs also cause 170,000 deaths per year. Their comprehensive impact on all aspects of daily life means that the presence of NTDs costs affected countries billions of dollars per year in lost productivity, out-of-pocket expenses, and reduced socioeconomic and educational attainment. 

Currently, 1.7b individuals are affected by such diseases. However, the treatments and knowledge required to eliminate these diseases are readily available, with the annual cost of treatment per individual averaging 50 cents per year. Demonstrating the uniquely cost-effective impact of NTD treatment, studies have shown treatment is the single most efficient means of improving children’s school attendance and capacity to learn. A recent report by Deloitte on Nigeria showcases the significant gains affected economies stand to make should NTDs be eliminated, with Nigeria’s economy estimated to receive an $18.9b boost from now until 2030. The report is available to view here - https://www2.deloitte.com/za/en/nigeria/pages/strategy/articles/Ending_The_Neglect.html

The END Fund helps ensure those at risk of NTDs need not experience such preventable suffering but can live healthy and prosperous lives instead. We do so by working in close partnership with stakeholders across the global NTD community to identify and fulfill gaps and needs in NTD funding, design programs, strengthen the capacity of local actors, provide technical support, and assist with monitoring and evaluation, amongst various additional activities. Our work helps children stay healthy and in school, prevents advanced cases that cause disability and restrain individuals' productive potential, and alleviates the disproportionate disease burden faced by women and girls, as well as the economic burden of disease on families. We have distributed more than 1.2b treatments since our founding in 2012, with 118m individuals treated in 2021 alone.

We envision living in a world in which all have the opportunity to achieve their full potential, with these diseases that have plagued humans for millennia confined to history once and for all.

The END Fund

LEEP advocates to prevent lead poisoning and improve the health, wellbeing, and potential of children worldwide. 

LEEP advocates for regulation on lead paint to reduce lead poisoning and improve the health, wellbeing, and potential of children worldwide. Lead poisoning is a colossal issue causing disability in 815 million children worldwide.

Currently, we are working on programs in Malawi, Zimbabwe, Madagascar and Pakistan, and are looking to expand to another 7 countries in the next year.

To learn more about our work, check out:
https://leadelimination.org/projects/
https://leadelimination.org/faqs/
https://leadelimination.org/blog/

Thank you for helping us to address the problem of lead poisoning, and improve the health of children worldwide.

Lead Exposure Elimination Project (LEEP)

One of GiveWell's top charities for the past several years, AMF provides anti-malarial bednets to people in need. 

From Givewell: 
What do they do? AMF (againstmalaria.com) provides funding for long-lasting insecticide-treated net (LLIN) distributions (for protection against malaria) in developing countries. (More)

Does it work? There is strong evidence that distributing LLINs reduces child mortality and malaria cases. AMF conducts post-distribution surveys of completed distributions to determine whether LLINs have reached their intended destinations and how long they remain in good condition. AMF's post-distribution surveys have generally found positive results but have some methodological limitations. (More)

What do you get for your dollar? We estimate that the cost to purchase and distribute an AMF-funded net is $4.95, or $4.65 excluding in-kind contributions from governments. The numbers of deaths averted and other benefits of distributing LLINs are a function of a number of difficult-to-estimate factors, which we discuss in detail below. (More)

Is there room for more funding? We believe that AMF is likely to be constrained by funding. We estimate that AMF could use up to an additional $37.8 million to support LLIN distributions that will occur between now and late 2023. 

AMF is recommended because of its:

Focus on a program with excellent evidence of effectiveness and cost-effectiveness.
Processes for ensuring that nets reach their intended recipients and monitoring whether they remain in homes and in good condition over the long-term.
Room for more funding – we believe AMF will be able to use additional funds to deliver additional nets.
Transparency – AMF shares significant information about its work with us and we are able to closely follow and understand its work.

The Against Malaria Foundation

Delivering unconditional cash directly to the world's poorest households via secure mobile transfers. 

Since 2009, GiveDirectly has delivered more than $580 million in unconditional cash transfers to families in need. These one-time cash transfers allow recipients to invest in what they need most and have been shown to improve their earnings, children’s school attendance, health, nutrition, and mental well-being.
 
GiveDirectly uses government data to target villages where most or all residents are living in extreme poverty, defined by the World Bank as earning under $2.15/day. In-country GiveDirectly staff enroll one member of each household in the entire village to receive a one-time transfer of about $1,000 USD sent in two installments using mobile money. Recipients can then withdraw the mobile funds as cash with local agents and use the funds to invest in what they need – whether it’s on starting a business, education, making their home safer/sturdier, healthcare, or livestock.
 
GiveDirectly uses rigorous experimental research (randomized controlled trials) to measure the impact of their unconditional cash programs and answer public policy questions, generating evidence on key design and implementation questions across varied contexts. You can find over 300 studies on the positive impacts of cash transfers in GiveDirectly’s Cash Research Explorer.

GiveDirectly

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We are a nonprofit, so instead of charging fees we rely on the generosity of donors like you.

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